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SKU: E-AB-52081_20μL-ES
TJP1 Polyclonal Antibody, 20 μL
Tight junction (or zonula occludens) form the continuous intercellular barrier between epithelial and endothelial cells,which is required to separate tissue spaces and regulate selective movement of solutes across the epithelium and endothelium . ZO-1 (also known as TJP1) is a peripheral membrane phosphoprotein located on the cytoplasmic face and is expressed in tight junctions of both epithelial and endothelial cells . It binds the transmembrane proteins occludin and the claudins linking them to cytoskeletal actin . ZO-1 belongs to a family of multidomain proteins known as the membrane-associated guanylate kinase homologs (MAGUKs). It is a pivotal tight junction protein and may be involved in signalling mechanisms regulating cell proliferation and differentiation .
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Product Specification
Basic Information
Brands:Elabscience
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Place of Origin:China
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Shelf Life:12 months
Storage:Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.
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Dilution:IHC 1:30-1:150
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Application:IHC
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Research Areas:Cancer;Tags and Cell Markers
Species Reactivity:Human;Mouse;Rat
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Target Synonym:Tight junction protein 1;Tight junction protein ZO-1;Tight junction protein ZO1;TJP1;zo-1;Zo1;ZO1;Zona occludens 1;Zona occludens 1 protein;Zona occludens protein 1;Zonula occludens 1 protein;Zonula occludens protein 1
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Buffer:PBS with 0.05% NaN3 and 40% Glycerol,pH7.4
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Conjugation:Unconjugated
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