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SKU: E-AB-52113_20μL-ES
SPI1 Polyclonal Antibody, 20 μL
SPI1 encodes an ETS-domain transcription factor that activates gene expression during myeloid and B-lymphoid cell development. The nuclear protein binds to a purine-rich sequence known as the PU-box found near the promoters of target genes, and regulates their expression in coordination with other transcription factors and cofactors. The protein can also regulate alternative splicing of target genes. Multiple transcript variants encoding different isoforms have been found for this gene.SPI1 (Spi-1 Proto-Oncogene) is a Protein Coding gene. Diseases associated with SPI1 include Inflammatory Diarrhea and Interdigitating Dendritic Cell Sarcoma. Among its related pathways are Validated targets of C-MYC transcriptional repression and C-MYB transcription factor network. GO annotations related to this gene include transcription factor activity, sequence-specific DNA binding and RNA binding. An important paralog of this gene is SPIB.
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Product Specification
Basic Information
Brands:Elabscience
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Place of Origin:China
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Calculated Molecular Weight:31 kDa
Observed Molecular Weight:Refer to figures
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Shelf Life:12 months
Storage:Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.
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Calculated Molecular Weight:31 kDa
Dilution:WB 1:500-1:2000
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Application:WB
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Research Areas:Cancer;Epigenetics and Nuclear Signaling;Immunology
Species Reactivity:Human;Mouse;Rat
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Target Synonym:transcription factor spi1;31 kDa Transforming Protein;31 kDa-transforming protein;cb1086;Hematopoietic transcription factor PU.1;OF;oncogene spi1;PU.1;SFFV virus-induced murine erythroleukemia oncogene;mouse;homolog of;SFPI1;si:by184l24.2;SPI 1;SPI 1 proto oncogene;SPI A;Spi1;SPI1;Spleen focus forming virus (SFFV) proviral integration oncogene spi1;Spleen focus forming virus proviral integration oncogene spi1;Transcription factor PU.1
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Buffer:PBS with 0.05% NaN3 and 40% Glycerol,pH7.4
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Conjugation:Unconjugated
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