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SKU: E-AB-52774_60μL-ES
SLC26A3 Polyclonal Antibody, 60 μL
The protein encoded by this gene is a transmembrane glycoprotein that transports chloride ions across the cell membrane in exchange for bicarbonate ions. It is localized to the mucosa of the lower intestinal tract, particularly to the apical membrane of columnar epithelium and some goblet cells. The protein is essential for intestinal chloride absorption, and mutations in this gene have been associated with congenital chloride diarrhea.SLC26A3 (Solute Carrier Family 26 Member 3) is a Protein Coding gene. Diseases associated with SLC26A3 include Diarrhea 1, Secretory Chloride, Congenital and Congenital Chloride Diarrhea. Among its related pathways are Transport of glucose and other sugars, bile salts and organic acids, metal ions and amine compounds and Pancreatic secretion. GO annotations related to this gene include transcription factor activity, sequence-specific DNA binding and transcription cofactor activity. An important paralog of this gene is SLC26A4.
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Product Specification
Basic Information
Brands:Elabscience
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Place of Origin:China
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Calculated Molecular Weight:85 kDa
Observed Molecular Weight:Refer to figures
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Shelf Life:12 months
Storage:Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.
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Calculated Molecular Weight:85 kDa
Dilution:WB 1:500-1:2000;IHC 1:25-1:100
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Application:WB;IHC
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Research Areas:Cancer;Metabolism;Signal Transduction
Species Reactivity:Human;Mouse;Rat
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Target Synonym:Chloride anion exchanger;CLD;Congenital chloride diarrhea;Down regulated in adenoma;Down regulated in adenoma protein;Down-regulated in adenoma;DRA;Protein DRA;S26A3;SLC26A3;Solute carrier family 26 member 3
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Buffer:PBS with 0.05% NaN3 and 40% Glycerol,pH7.4
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Conjugation:Unconjugated
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