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SKU: E-AB-12870_20μL-ES
SLC22A17 Polyclonal Antibody, 20 μL
Cell surface receptor for LCN2 (24p3) that plays a key role in iron homeostasis and transport. Able to bind iron-bound LCN2 (holo-24p3), followed by internalization of holo-24p3 and release of iron, thereby increasing intracellular iron concentration and leading to inhibition of apoptosis. Also binds iron-free LCN2 (apo-24p3), followed by internalization of apo-24p3 and its association with an intracellular siderophore, leading to iron chelation and iron transfer to the extracellular medium, thereby reducing intracellular iron concentration and resulting in apoptosis.
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Product Specification
Basic Information
Brands:Elabscience
Model Number:
Place of Origin:China
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Shipping:The product is shipped with ice pack,upon receipt,store it immediately at the temperature recommended.
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Concentration:0.3 mg/mL
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Shelf Life:12 months
Storage:Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.
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Dilution:IHC 1:25-1:100
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Application:IHC
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Research Areas:Cancer;Metabolism;Signal Transduction
Species Reactivity:Human;Mouse;Rat
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Target Synonym:24p3 receptor;24p3R;BOCT;BOIT;Brain type organic cation transporter;Brain-type organic cation transporter;hBOIT;Lipocalin-2 receptor;Neutrophil gelatinase associated lipocalin receptor;Neutrophil gelatinase-associated lipocalin receptor;NGAL receptor;NgalR;NGALR2;NGALR3;OTTHUMP00000082690;OTTHUMP00000082691;Potent brain type organic ion transporter;S22AH;Slc22a17;Solute carrier family 22 member 17;Solute carrier family 22 organic cation transporter member 17
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Buffer:PBS with 0.05% sodium azide and 50% glycerol, PH7.4
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Clonality:Polyclonal
Conjugation:Unconjugated
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