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SKU: E-AB-52745_120μL-ES
SCRN2 Polyclonal Antibody, 120 μL
The SCRN (Secernin) gene family has three vertebrate paralogs, i.e. SCRN1, SCRN2 and SCRN3, which are closely linked to human HOXA, HOXB and HOXD cluster, respectively. SCRN2 (secernin-2) is a 425 amino acid protein that belongs to the peptidase C69 family and the Secernin subfamily. Vertebrate SCRN genes showed a topology of the form (A)(BC), i.e. (Hsa2 Hsa7)(Hsa17), with SCRN2 falling outside the SCRN3–SCRN1 cluster. The SCRN2 gene is conserved in dog, cow, mouse, rat and zebrafish, and maps to human chromosome 17q21.32. Chromosome 17 makes up over 2.5% of the human genome with about 81 million bases encoding over 1,200 genes. Chromosome 17 is linked to neurofibromatosis, a condition characterized by neural and epidermal lesions, and dysregulated Schwann cell growth. Alexander disease, Birt-Hogg-Dube syndrome and Canavan disease are also associated with chromosome 17.
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Product Specification
Basic Information
Brands:Elabscience
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Place of Origin:China
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Calculated Molecular Weight:47 kDa
Observed Molecular Weight:Refer to figures
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Shelf Life:12 months
Storage:Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.
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Calculated Molecular Weight:47 kDa
Dilution:WB 1:500-1:2000;IHC 1:50-1:300
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Application:WB;IHC
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Research Areas:Cell Biology
Species Reactivity:Human;Mouse;Rat
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Target Synonym:scrn2;SCRN2;Secernin 2;Secernin-2;Ses2
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Buffer:PBS with 0.05% NaN3 and 40% Glycerol,pH7.4
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Conjugation:Unconjugated
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