SKU: PKSH033191_10μg-ES

Recombinant Human UBE2V2/DDVIT1 Protein (His Tag), 10 μg

Ubiquitin-Conjugating Enzyme E2 Variant 2 (UBE2V2) is an enzyme that belongs to the ubiquitin-conjugating enzyme family. UBE2V2 can be detected in the placenta, colon, liver, and skin. It forms a heterodimer with UBE2N. The UBE2V2/UBE2N heterodimer catalyzes the synthesis of non-canonical poly-ubiquitin chains and which leads to protein degradation by the proteasome. UBE2V2 mediates transcriptional activation of target genes. It plays a role in the control of progress through the cell cycle and differentiation. It also plays a role in the error-free DNA repair pathway and contributes to the survival of cells after DNA damage.

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Product Specification

Basic Information

Brands:Elabscience

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Place of Origin:China

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Reconstitution:Not Applicable

Shipping:This product is provided as liquid. It is shipped at frozen temperature with blue ice/gel packs. Upon receipt, store it immediately at < - 20°C.

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Calculated Molecular Weight:18.5 kDa

Observed Molecular Weight:18 kDa

Purity: > 95 % as determined by reducing SDS-PAGE.

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Storage:Store at < -20°C, stable for 6 months. Please minimize freeze-thaw cycles.

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Calculated Molecular Weight:18.5 kDa

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Endotoxin: < 1.0 EU per μg of the protein as determined by the LAL method.

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Research Areas:Cell biology;epigenetics and nuclear signal

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Bio-activity:Not validated for activity

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Formulation:Supplied as a 0.2 μm filtered solution of 50mm HEPES,150mM NaCl, pH 7.0.

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