SKU: PKSH033148_10μg-ES

Recombinant Human TPI1/TIM Protein (His Tag), 10 μg

Triose-phosphate isomerase, also named Triose-phosphate isomerase, TPI and TIM, is an enzyme that catalyzes the reversible interconversion of the triose phosphate isomers dihydroxyacetone phosphate and D-glyceraldehyde 3-phosphate. TPI has been found in nearly every organism searched for the enzyme, including animals such as mammals and insects as well as in fungi, plants, and bacteria. However, some bacteria that do not perform glycolysis, like ureaplasmas, lack TPI. TPI plays an important role in glycolysis and is essential for efficient energy production. TPI deficiency is an autosomal recessive disorder and the most severe clinical disorder of glycolysis. Triose phosphate isomerase deficiency is associated with neonatal jaundice, chronic hemolytic anemia, progressive neuromuscular dysfunction, cardiomyopathy and increased susceptibility to infection and characterized by chronic hemolytic anemia.

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Product Specification

Basic Information

Brands:Elabscience

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Place of Origin:China

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Sterile Status:

Reconstitution:Not Applicable

Shipping:This product is provided as liquid. It is shipped at frozen temperature with blue ice/gel packs. Upon receipt, store it immediately at < - 20°C.

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Calculated Molecular Weight:28.8 kDa

Observed Molecular Weight:30 kDa

Purity: > 95 % as determined by reducing SDS-PAGE.

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Storage:Store at < -20°C, stable for 6 months. Please minimize freeze-thaw cycles.

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Calculated Molecular Weight:28.8 kDa

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Endotoxin: < 1.0 EU per μg of the protein as determined by the LAL method.

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Research Areas:Signal Transduction;Cancer;metabolism;

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Formulation:Supplied as a 0.2 μm filtered solution of 20mM Tris-HCl, 1mM DTT, 10% Glycerol, pH 8.0.

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