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SKU: PKSH032894_10μg-ES
Recombinant Human PMM2 Protein (His Tag), 10 μg
Phosphomannomutase 2 (PMM2) is an enzyme that is a member of the highly variable methyltransferase superfamily. PMM2 is a cytoplasmic protein and catalyzes the isomerization of mannose 6-phosphate to mannose 1-phosphate.In addition, PMM2 involved in the synthesis of the GDP-mannose and dolichol-phosphate-mannose that required for a number of critical mannosyl transfer reactions. Defects in PMM2 can results in congenital disorder of glycosylation type 1A (CDG1A). Congenital disorders of glycosylation are metabolic deficiencies in glycoprotein biosynthesis that usually cause severe mental and psychomotor retardation.
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Product Specification
Basic Information
Brands:Elabscience
Model Number:
Place of Origin:China
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Sterile Status:
Reconstitution:Not Applicable
Shipping:This product is provided as liquid. It is shipped at frozen temperature with blue ice/gel packs. Upon receipt, store it immediately at < - 20°C.
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Calculated Molecular Weight:29.1 kDa
Observed Molecular Weight:29 kDa
Purity: > 95 % as determined by reducing SDS-PAGE.
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Storage:Store at < -20°C, stable for 6 months. Please minimize freeze-thaw cycles.
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Calculated Molecular Weight:29.1 kDa
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Endotoxin: < 1.0 EU per μg of the protein as determined by the LAL method.
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Research Areas:Signal Transduction;metabolism;
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Bio-activity:Not validated for activity
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Formulation:Supplied as a 0.2 μm filtered solution of 20mM Tris-HCl, 150mM NaCl, pH 8.0.
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