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SKU: PKSH032497_50μg-ES
Recombinant Human GSS Protein (His Tag), 50 μg
Glutathione Synthetase belongs to the eukaryotic GSH synthase family. Glutathione Synthetase is the second enzyme in the glutathione biosynthesis pathway. It catalyses the condensation of gamma-glutamylcysteine and glycine to form glutathione. Glutathione play an important role in a variety of biological functions, including detoxification of xenobiotics, protection of cells from oxidative damage by free radicals, and membrane transport. The protein functions as a homodimer to catalyze the second step of glutathione biosynthesis, which is the ATP-dependent conversion of gamma-L-glutamyl-L-cysteine to glutathione. Defects in Glutathione Synthetase can also cause the glutathione synthetase deficiency of erythrocytes, which is a mild form causing hemolytic anemia.
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Product Specification
Basic Information
Brands:Elabscience
Model Number:
Place of Origin:China
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Sterile Status:
Reconstitution:Not Applicable
Shipping:This product is provided as liquid. It is shipped at frozen temperature with blue ice/gel packs. Upon receipt, store it immediately at < - 20°C.
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Calculated Molecular Weight:53.5 kDa
Observed Molecular Weight:55 kDa
Purity: > 95 % as determined by reducing SDS-PAGE.
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Storage:Store at < -20°C, stable for 6 months. Please minimize freeze-thaw cycles.
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Calculated Molecular Weight:53.5 kDa
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Endotoxin: < 1.0 EU per μg of the protein as determined by the LAL method.
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Research Areas:Signal Transduction;Cell biology;Neuroscience;metabolism;
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Bio-activity:Not validated for activity
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Formulation:Supplied as a 0.2 μm filtered solution of 20mM Tris-HCl, 200mM NaCl, pH 7.5.
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