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SKU: E-AB-F1229J_100T-ES
PerCP/Cyanine5.5 Anti-Human CD279/PD-1 Antibody[EH12.2H7], 100 T
Programmed cell death 1 (PD-1), also known as CD279, is a 55 kD member of the immunoglobulin superfamily. CD279 contains the immunoreceptor tyrosine-based inhibitory motif (ITIM) in the cytoplasmic region and plays a key role in peripheral tolerance and autoimmune disease. CD279 is expressed predominantly on activated T cells, B cells, and myeloid cells. PD-L1 and PD-L2 are ligands of CD279 (PD-1) and are members of the B7 gene family. Evidence suggests overlapping functions for these two PD-1 ligands and their constitutive expression on some normal tissues and upregulation on activated antigen-presenting cells. Interaction of CD279 ligands results in inhibition of T cell proliferation and cytokine secretion.
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Product Specification
Basic Information
Brands:Elabscience
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Place of Origin:China
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Concentration:5 μL/Test
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Shelf Life:12 months
Storage:This product can be stored at 2-8°C for 12 months. Please protected from prolonged exposure to light and do not freeze.
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Application:FCM
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Research Areas:Cancer Biomarkers;Immunology;Inhibitory Molecules
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Target Synonym:PD1;PDCD1;Protein PD-1;hPD-1
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Clonality:Monoclonal
Conjugation:PerCP/Cyanine 5.5
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