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SKU: E-AB-F1235H_100T×2-ES
PE/Cyanine7 Anti-Mouse CD51 Antibody[RMV-7], 100 T×2
CD51 is a 140 kD protein, also known as αV integrin, vitronectin receptor, and integrin αV. It is a member of the integrin family, expressed on activated T cells, polymorphonuclear granulocytes, platelets, blastocysts, and osteoclasts. CD51 forms heterodimers by association with integrins β1, β3, β5 or β6; these complexes then act as receptors for multiple extracellular matrix proteins (ECM). The αvintegrin heterodimers have varied functions in development, stimulation/activation and homeostasis. The primary ligands for CD51 complexes are fibronectin, fibrinogen, vitronectin, thrombspondin, von Willebrand factor, and CD31. The RMV-7 antibody has been reported to block binding of CD51 to vitronectin, fibronectin, and CD31 in some cell types, as well as blocking LAK cell cytotoxicity.
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Product Specification
Basic Information
Brands:Elabscience
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Place of Origin:China
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Concentration:5 μL/Test
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Shelf Life:12 months
Storage:This product can be stored at 2-8°C for 12 months. Please protected from prolonged exposure to light and do not freeze.
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Application:FCM
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Research Areas:Angiogenesis;Cell Adhesion;Cell Biology;Costimulatory Molecules;Immunology;Innate Immunity;Stem Cells
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Target Synonym:ITGAV;Integrin alpha-V;Integrin αV chain;Vitronectin Receptor;αV integrin
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Clonality:Monoclonal
Conjugation:PE/Cyanine 7
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