SKU: E-AB-40651_25μL-ES

PAI1 Polyclonal Antibody, 25 μL

Serine protease inhibitor. Inhibits TMPRSS7. Is a primary inhibitor of tissue-type plasminogen activator (PLAT) and urokinase-type plasminogen activator (PLAU). As PLAT inhibitor, it is required for fibrinolysis down-regulation and is responsible for the controlled degradation of blood clots. As PLAU inhibitor, it is involved in the regulation of cell adhesion and spreading.Acts as a regulator of cell migration, independently of its role as protease inhibitor. It is required for stimulation of keratinocyte migration during cutaneous injury repair. It is involved in cellular and replicative senescence. Plays a role in alveolar type 2 cells senescence in the lung. Is involved in the regulation of cementogenic differentiation of periodontal ligament stem cells, and regulates odontoblast differentiation and dentin formation during odontogenesis.

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Product Specification

Basic Information

Brands:Elabscience

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Place of Origin:China

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Shipping:The product is shipped with ice pack,upon receipt,store it immediately at the temperature recommended.

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Calculated Molecular Weight:45 kDa

Observed Molecular Weight:47 kDa

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Shelf Life:12 months

Storage:Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.

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Calculated Molecular Weight:45 kDa

Dilution:WB 1:250-1:500

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Application:WB

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Research Areas:Cancer;Cell Biology;Metabolism

Species Reactivity:Rat

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Target Synonym:Plasminogen activator inhibitor 1; PAI-1; Endothelial plasminogen activator inhibitor; Serpin E1; SERPINE1; PLANH1

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Buffer:PBS with 0.02% sodium azide,1% protective protein and 50% glycerol,pH7.4

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Clonality:Polyclonal

Conjugation:Unconjugated

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