SKU: E-AB-62370_120μL-ES

METAP2 Polyclonal Antibody, 120 μL

The protein encoded by this gene is a member of the methionyl aminopeptidase family. The encoded protein functions both by protecting the alpha subunit of eukaryotic initiation factor 2 from inhibitory phosphorylation and by removing the amino-terminal methionine residue from nascent proteins. Increased expression of this gene is associated with various forms of cancer, and the anti-cancer drugs fumagillin and ovalicin inhibit the protein by irreversibly binding to its active site. Inhibitors of this gene have also been shown to be effective for the treatment of obesity. A pseudogene of this gene is located on chromosome 2. Several transcript variants encoding different isoforms have been found for this gene.

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Product Specification

Basic Information

Brands:Elabscience

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Place of Origin:China

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Shipping:The product is shipped with ice pack,upon receipt,store it immediately at the temperature recommended.

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Concentration:1mg/mL

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Calculated Molecular Weight:50kDa/52kDa

Observed Molecular Weight:60kDa

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Shelf Life:12 months

Storage:Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.

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Calculated Molecular Weight:50kDa/52kDa

Dilution:WB 1:200-1:2000

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Application:WB

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Research Areas:Cancer;Metabolism;Signal Transduction

Species Reactivity:Human;Mouse

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Buffer:PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

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Clonality:Polyclonal

Conjugation:Unconjugated

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