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SKU: E-AB-15058_120μL-ES
MCM3AP Polyclonal Antibody, 120 μL
The minichromosome maintenance protein 3 (MCM3) is one of the MCM proteins essential for the initiation of DNA replication. The protein encoded by this gene is a MCM3 binding protein. It was reported to have phosphorylation-dependent DNA-primase activity, which was up-regulated in antigen immunization induced germinal center. This protein was demonstrated to be an acetyltransferase that acetylates MCM3 and plays a role in DNA replication. The mutagenesis of a nuclear localization signal of MCM3 affects the binding of this protein with MCM3, suggesting that this protein may also facilitate MCM3 nuclear localization. This gene is expressed in the brain or in neuronal tissue. An allelic variant encoding amino acid Lys at 915, instead of conserved Glu, has been identified in patients with mild intellectual disability.
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Product Specification
Basic Information
Brands:Elabscience
Model Number:
Place of Origin:China
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Shipping:The product is shipped with ice pack,upon receipt,store it immediately at the temperature recommended.
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Concentration:0.4 mg/mL
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Calculated Molecular Weight:218kDa
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Shelf Life:12 months
Storage:Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.
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Calculated Molecular Weight:218kDa
Dilution:WB 1:500-1:2000;IHC 1:50-1:200
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Application:WB;IHC
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Research Areas:Cell Biology;Epigenetics and Nuclear Signaling
Species Reactivity:Human
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Target Synonym:80 kDa MCM3 associated protein;80 kDa MCM3-associated protein;FLJ44336;FLJ45306;Germinal center associated nuclear protein;KIAA0572;MAP80;MCM3 import protein;MCM3 minichromosome maintenance deficient 3 associated protein;MCM3A;MCM3A;Mcm3ap;Minichromosome maintenance complex component 3 associated protein;Minichromosome maintenance deficient 3 associated protein;Minichromosome maintenance protein 3 associated protein;Protein GANP;SAC3
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Buffer:PBS with 0.05% sodium azide and 50% glycerol, PH7.4
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Clonality:Polyclonal
Conjugation:Unconjugated
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