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SKU: E-AB-52736_20μL-ES
KRR1 Polyclonal Antibody, 20 μL
The SSU is a large ribonucleoprotein consisting of at least 40 proteins and the U3 small nucleolar RNA. It is involved in pre-rRNA processing and ribosome assembly. The SSU is necessary for the biogenesis of the 18S rRNA. Cells that are depleted of SSU proteins will arrest in the G1 phase of the cell cycle. KRR1, also known as HRB2 (HIV-1 Rev binding protein 2) or RIP-1 (Rev interacting protein 1), is a nonribosomal component of the small subunit processome (SSU). KRR1 is 381 amino acids in length and is evolutionarily conserved among human, yeast, fly, nematode and rice. KRR1 localizes to the nucleolus and is highly expressed in dividing cells. It contains one conserved KH domain (RNA-binding motif) and is a crucial component of the SSU, required for both rRNA maturation and ribosome biogenesis.
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Product Specification
Basic Information
Brands:Elabscience
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Place of Origin:China
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Shelf Life:12 months
Storage:Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.
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Dilution:IHC 1:50-1:300
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Application:IHC
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Research Areas:Cancer;Epigenetics and Nuclear Signaling;Immunology;Tags and Cell markers
Species Reactivity:Human;Mouse
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Target Synonym:HIV 1 Rev binding protein 2;HIV-1 Rev-binding protein 2;HRB2;KRR1;KRR1 small subunit processome component homolog;KRR1; small subunit (SSU) processome component; homolog (yeast);KRR1;Rev interacting protein 1;Rev-interacting protein 1;RIP 1 ;Rip-1
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Buffer:PBS with 0.05% NaN3 and 40% Glycerol,pH7.4
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Conjugation:Unconjugated
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