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SKU: E-AB-52051_120μL-ES
ITPR2 Polyclonal Antibody, 120 μL
Inositol 1,4,5-triphosphate (IP3) functions as a second messenger for a myriad of extracellular stimuli including hormones, growth factors and neurotransmitters. Receptor tyrosine kinases indirectly increase the intracellular levels of IP3 through the activation of phospholipases such as phospholipase C (PLC), which convert phosphatidylinositol-4,5 bisphosphate into IP3 and diacylglycerol (DAG). The inositol 1,4,5-triphosphate receptor, IP3R, acts as an inositol triphosphate (IP3)-gated calcium release channel in a variety of cell types. Three IP3 receptor subtypes have been described and are designated IP3R-I, IP3R-II and IP3R-III. IP3R-I is the predominant IP3R subtype expressed in neuronal tissues and the central nervous system, but is also expressed at high levels in the liver.
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Product Specification
Basic Information
Brands:Elabscience
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Place of Origin:China
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Shelf Life:12 months
Storage:Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.
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Dilution:IHC 1:50-1:300
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Application:IHC
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Research Areas:Cancer;Metabolism;Signal Transduction
Species Reactivity:Human;Mouse;Rat
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Target Synonym:4;5-trisphosphate receptor;Inositol 1 4 5 trisphosphate receptor type 2;Inositol 1;4;5-trisphosphate receptor type 2;Inositol 145 trisphosphate receptor type 2;InsP3 R2;InsP3R2;IP3 R2;IP3 receptor;IP3 receptor isoform 2;IP3R 2;IP3R2;ITPR 2;Itpr2;ITPR2;Type 2 inositol 1 4 5 trisphosphate receptor;Type 2 inositol 1;Type 2 inositol 145 trisphosphate receptor;Type 2 InsP3 receptor
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Buffer:PBS with 0.05% NaN3 and 40% Glycerol,pH7.4
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Conjugation:Unconjugated
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