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SKU: AN000380P_1mg-ES
HO1/HMOX1 Polyclonal Antibody, 1 mg
Heme Oxygenase (HO),also known as HMOX,is the rate limiting enzyme in the breakdown of heme into Biliverdin,CO,and iron. There are two major isoforms of this enzyme,HO-1 and HO-2. Both have similar enzymatic activity,however,HO-1 is rapidly inducible,while HO-2 is constitutively expressed. Inducers of HO-1 include cell stressors such as oxidative stress,infection,hypoxia,and cytotoxic agents. The reaction products generated by HO-1 activity are biologically active,and the enzyme has a broad range of putative roles. For instance,Biliverdin is an antioxidant with cytoprotective and anti-inflammatory properties,and CO has the potential to suppress inflammation and apoptosis. Because of these activities,HO-1 has received much attention as a therapeutic target for a range of pathological processes.
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Product Specification
Basic Information
Brands:Elabscience
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Place of Origin:China
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Shipping:The product is shipped with ice pack,upon receipt,store it immediately at the temperature recommended.
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Concentration:1 mg/mL
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Calculated Molecular Weight:33kDa
Observed Molecular Weight:25kDa
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Shelf Life:12 months
Storage:Store at 4°C valid for 12 months or -20°C valid for long term storage, avoid freeze / thaw cycles.
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Calculated Molecular Weight:33kDa
Dilution:WB 1:500-1:1000;IHC 1:500-1:1000;ELISA Capture 2-8 μg/mL;ELISA Detector 0.1-0.4 μg/mL
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Application:WB;IHC;ELISA Capture/Detector
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Research Areas:Neuroscience;Cardiovascular;Signal Transduction;Epigenetics and Nuclear Signaling;Cancer;Metabolism
Species Reactivity:Human;Mouse
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Target Synonym:Heme oxygenase 1;HO-1;HMOX1;HO;HO1;EC:1.14.14.18
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Buffer:Phosphate buffered solution, pH 7.2, containing 0.05% proclin 300.
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Clonality:Polyclonal
Conjugation:Unconjugated
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