SKU: E-AB-F1286C_50T-ES

FITC Anti-Mouse CD172a/SIRPα Antibody[P84], 50 T

CD172a, also known as SIRPα, is a type I transmembrane protein with one V-set Ig-like and two C-set Ig-like domains in the extracellular portion, and two ITIM motifs and a proline-rich region in the cytoplasmic tail. CD172a is expressed by monocytes, macrophages, myeloid cells, and neuronal tissue. The phosphorylation of SIRPα ITIMs induces the recruitment and activation of the tyrosine phosphatases PTPN6 and PTPN11, resulting in the negative regulation of several biological processes. The ligands of CD172a are CD47, SP-A, and SP-D.

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Product Specification

Basic Information

Brands:Elabscience

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Place of Origin:China

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Shelf Life:12 months

Storage:This product can be stored at 2-8°C for 12 months. Please protected from prolonged exposure to light and do not freeze.

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Application:FCM

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Research Areas:Cell Adhesion;Cell Biology;Immunology;Signal Transduction

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Target Synonym:BIT;CD172 antigen-like family member A;P84;PTPNS1;SHPS-1;SIRPα

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Conjugation:FITC

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