SKU: D-AB-10418L_100μL-ES

FAS/CD95 Polyclonal Antibody, 100 μL

Fas (CD95/APO-1) is a transmembrane glycoprotein belonging to the tumor necrosis factor (TNF) receptor superfamily. It can mediate apoptosis by ligation with an agonistic anti-Fas antibody or Fas ligand. Stimulation of Fas results in the aggregation of its intracellular death domains,leading to the formation of the death-inducing signaling complex (DISC). FAS-mediated apoptosis may have a role in the induction of peripheral tolerance,in the antigen-stimulated suicide of mature T-cells,or both. The molecular mass of native Fas is 38 kDa,the high molecular weight form (40-55 kDa) of Fas is due to glycosylation.

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Product Specification

Basic Information

Brands:Elabscience

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Place of Origin:China

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Shipping:The product is shipped with ice pack,upon receipt,store it immediately at the temperature recommended.

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Concentration:1 mg/mL

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Calculated Molecular Weight:37kDa

Observed Molecular Weight:38-45kDa

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Shelf Life:12 months

Storage:Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.

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Calculated Molecular Weight:37kDa

Dilution:WB 1:250-1:500

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Application:WB

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Research Areas:Cancer;Cell Biology;Immunology

Species Reactivity:Human

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Target Synonym:ALPS1A;APO 1;Apo 1 antigen; APT1;CD95;FAS;FAS/CD95;FAS1;FASLG receptor; FASTM; TNFRSF6

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Buffer:PBS with 0.02% sodium azide,1% protective protein and 50% glycerol,pH7.4

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Clonality:Polyclonal

Conjugation:Unconjugated

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