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SKU: E-AB-15083_20μL-ES
CD42b Polyclonal Antibody, 20 μL
Glycoprotein Ib (GP Ib) is a platelet surface membrane glycoprotein composed of a heterodimer, an alpha chain and a beta chain, that is linked by disulfide bonds. The Gp Ib functions as a receptor for von Willebrand factor (VWF). The complete receptor complex includes noncovalent association of the alpha and beta subunits with platelet glycoprotein IX and platelet glycoprotein V. The binding of the GP Ib-IX-V complex to VWF facilitates initial platelet adhesion to vascular subendothelium after vascular injury, and also initiates signaling events within the platelet that lead to enhanced platelet activation, thrombosis, and hemostasis. This gene encodes the alpha subunit. Mutations in this gene result in Bernard-Soulier syndromes and platelet-type von Willebrand disease. The coding region of this gene is known to contain a polymophic variable number tandem repeat (VNTR) domain that is associated with susceptibility to nonarteritic anterior ischemic optic neuropathy.
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Product Specification
Basic Information
Brands:Elabscience
Model Number:
Place of Origin:China
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Shipping:The product is shipped with ice pack,upon receipt,store it immediately at the temperature recommended.
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Concentration:0.3 mg/mL
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Shelf Life:12 months
Storage:Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.
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Dilution:IHC 1:50-1:200
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Application:IHC
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Research Areas:Cancer;Cardiovascular;Immunology
Species Reactivity:Human
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Target Synonym:Antigen CD42b alpha;BDPLT1;BDPLT3;BSS;CD 42b;CD42b alpha;CD42B;CD42b antigen;DBPLT3;GLYCOCALICIN;Glycoprotein Ib (platelet) alpha polypeptide;Glycoprotein Ibalpha;GP Ib alpha;GP1B;GP1BA;GPIb alpha;GPIbA;MGC34595;Platelet glycoprotein Ib alpha chain;Platelet glycoprotein Ib alpha polypeptide;Platelet membrane glycoprotein 1b alpha subunit;VWDP
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Buffer:PBS with 0.05% sodium azide and 50% glycerol, PH7.4
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Clonality:Polyclonal
Conjugation:Unconjugated
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