SKU: E-AB-16228_200μL-ES

CAV1 Polyclonal Antibody, 200 μL

The scaffolding protein encoded by this gene is the main component of the caveolae plasma membranes found in most cell types. The protein links integrin subunits to the tyrosine kinase FYN, an initiating step in coupling integrins to the Ras-ERK pathway and promoting cell cycle progression. The gene is a tumor suppressor gene candidate and a negative regulator of the Ras-p42/44 mitogen-activated kinase cascade. Caveolin 1 and caveolin 2 are located next to each other on chromosome 7 and express colocalizing proteins that form a stable hetero-oligomeric complex. Mutations in this gene have been associated with Berardinelli-Seip congenital lipodystrophy. Alternatively spliced transcripts encode alpha and beta isoforms of caveolin 1.

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Product Specification

Basic Information

Brands:Elabscience

Model Number:

Place of Origin:China

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Shipping:The product is shipped with ice pack,upon receipt,store it immediately at the temperature recommended.

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Concentration:0.5 mg/mL

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Calculated Molecular Weight:20kDa

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Shelf Life:12 months

Storage:Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.

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Calculated Molecular Weight:20kDa

Dilution:WB 1:500-1:2000

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Application:WB

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Research Areas:Cancer;Cardiovascular;Metabolism;Signal Transduction;Tags and Cell Markers

Species Reactivity:Human;Mouse;Rat

Reactivity:

Target Synonym:BSCL3;CAV;CAV1;CAV1;caveolae protein;22 kD;caveolin 1 alpha isoform;caveolin 1 beta isoform;Caveolin 1 caveolae protein 22kDa;Caveolin-1;Caveolin1;cell growth-inhibiting protein 32;CGL3;LCCNS;MSTP085;OTTHUMP00000025031;PPH3;VIP 21;VIP21

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Buffer:PBS with 0.05% sodium azide and 50% glycerol, PH7.4

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Clonality:Polyclonal

Conjugation:Unconjugated

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