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SKU: E-AB-10130_20μL-ES
APEX1 Polyclonal Antibody, 20 μL
Apurinic/apyrimidinic (AP) sites occur frequently in DNA molecules by spontaneous hydrolysis, by DNA damaging agents or by DNA glycosylases that remove specific abnormal bases. AP sites are pre-mutagenic lesions that can prevent normal DNA replication so the cell contains systems to identify and repair such sites. Class II AP endonucleases cleave the phosphodiester backbone 5' to the AP site. This gene encodes the major AP endonuclease in human cells. Splice variants have been found for this gene; all encode the same protein.
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Product Specification
Basic Information
Brands:Elabscience
Model Number:
Place of Origin:China
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Shipping:The product is shipped with ice pack,upon receipt,store it immediately at the temperature recommended.
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Concentration:0.1 mg/mL
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Calculated Molecular Weight:36kDa
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Shelf Life:12 months
Storage:Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.
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Calculated Molecular Weight:36kDa
Dilution:WB 1:500-1:2000
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Application:WB
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Research Areas:Cancer;Cardiovascular;Epigenetics and Nuclear Signaling
Species Reactivity:Human;Mouse;Rat
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Target Synonym:AP endonuclease 1;AP endonuclease class I;AP lyase;APE 1;APE;APE-1;APEN;APEX 1;APEX;APEX nuclease (multifunctional DNA repair enzyme) 1;Apex nuclease 1;APEX nuclease;APEX1;APEX1;Apurinic endonuclease;Apurinic-apyrimidinic endonuclease 1;Apurinic/apyrimidinic (abasic) endonuclease;Apurinic/apyrimidinic endonuclease 1;Apurinic/apyrimidinic exonuclease;APX;BAP1;Deoxyribonuclease (apurinic or apyrimidinic);DNA (apurinic or apyrimidinic site) lyase;DNA-(apurinic or apyrimidinic site) lyase;mitochondrial;EC 4.2.99.18;HAP 1;HAP1;Human Apurinic endonuclease 1;MGC139790;Multifunctional DNA repair enzyme;Redox factor 1;Redox factor-1;REF 1;REF 1 protein;REF-1;REF1;REF1 protein
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Buffer:PBS with 0.05% sodium azide and 50% glycerol, PH7.4
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Clonality:Polyclonal
Conjugation:Unconjugated
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