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SKU: E-AB-10123_60μL-ES
AIFM1 Polyclonal Antibody, 60 μL
This gene encodes a flavoprotein essential for nuclear disassembly in apoptotic cells, and it is found in the mitochondrial intermembrane space in healthy cells. Induction of apoptosis results in the translocation of this protein to the nucleus where it affects chromosome condensation and fragmentation. In addition, this gene product induces mitochondria to release the apoptogenic proteins cytochrome c and caspase-9. Mutations in this gene cause combined oxidative phosphorylation deficiency 6, which results in a severe mitochondrial encephalomyopathy. Alternative splicing results in multiple transcript variants. A related pseudogene has been identified on chromosome 10.
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Product Specification
Basic Information
Brands:Elabscience
Model Number:
Place of Origin:China
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Shipping:The product is shipped with ice pack,upon receipt,store it immediately at the temperature recommended.
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Concentration:0.2 mg/mL
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Calculated Molecular Weight:67kDa
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Shelf Life:12 months
Storage:Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.
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Calculated Molecular Weight:67kDa
Dilution:WB 1:500-1:2000;IHC 1:25-1:100
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Application:WB;IHC
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Research Areas:Cancer;Cell Biology;Epigenetics and Nuclear Signaling;Metabolism
Species Reactivity:Human;Mouse;Rat
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Target Synonym:AIFM1;AIFM1;Apoptosis inducing factor 1;mitochondrial;Apoptosis inducing factor;Apoptosis inducing factor;mitochondrion associated;1;Apoptosis-inducing factor 1;CMTX4;COWCK;COXPD6;Harlequin;Hq;mAIF;MGC111425;MGC5706;mitochondrial;Neuropathy;axonal motor-sensory;with deafness and mental retardation;neuropathy;axonal;motor-sensory with deafness and mental retardation (Cowchock syndrome);PDCD 8;PDCD8;Programmed cell death 8 (apoptosis inducing factor);Programmed cell death 8;Programmed cell death 8 isoform 1;Programmed cell death 8 isoform 2;Programmed cell death 8 isoform 3;Programmed cell death protein 8;Programmed cell death protein 8 mitochondrial;Programmed cell death protein 8 mitochondrial precursor;Programmed cell death protein 8 mitochondrial precursor;Striatal apoptosis inducing factor
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Buffer:PBS with 0.05% sodium azide and 50% glycerol, PH7.4
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Clonality:Polyclonal
Conjugation:Unconjugated
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