SKU: E-AB-18828_60μL-ES

ADRM1 Polyclonal Antibody, 60 μL

The 26S proteasome is a key component of the ubiquitin-proteasome system,a process responsible for the majority of cellular protein degradation. hRpn13 (also termed ADRM1 or GP110) is a novel 46-kDa subunit of its 19S regulatory complex. hRpn13 binds directly to the proteasome-associated deubiquitinating enzyme,UCH37,and enhances its isopeptidase activity. Overexpression of hRpn13 promotes the activity of the ubiquitin-proteasome system and modulates the influence of osteoblasts on osteoclasts by controlling the stability of regulatory proteins in osteoblasts.

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Product Specification

Basic Information

Brands:Elabscience

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Place of Origin:China

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Shipping:The product is shipped with ice pack,upon receipt,store it immediately at the temperature recommended.

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Concentration:1.26 mg/mL

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Shelf Life:12 months

Storage:Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.

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Dilution:IHC 1:50-1:300

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Application:IHC

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Research Areas:Cancer;Signal Transduction

Species Reactivity:Human;Mouse;Rat

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Target Synonym:110 kDa cell membrane glycoprotein; adhesion regulating molecule 1; Adhesion-regulating molecule 1; ADRM 1; Adrm1; ADRM1; ARM 1; ARM-1; ARM1; Gp110; hRpn13; M(r) 110; 000 surface antigen; Proteasomal ubiquitin receptor ADRM1; proteasome regulatory particle non ATPase 13; Proteasome regulatory particle non-ATPase 13; Regulatory particle non ATPase 13; Rpn13; Rpn13 homolog

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Buffer:PBS with 0.05% NaN3 and 40% Glycerol,pH7.4

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Clonality:Polyclonal

Conjugation:Unconjugated

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