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SKU: E-AB-12935_200μL-ES
ABCA4 Polyclonal Antibody, 200 μL
The membrane-associated protein encoded by this gene is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intracellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). This protein is a member of the ABC1 subfamily. Members of the ABC1 subfamily comprise the only major ABC subfamily found exclusively in multicellular eukaryotes. This protein is a retina-specific ABC transporter with N-retinylidene-PE as a substrate. It is expressed exclusively in retina photoreceptor cells, indicating the gene product mediates transport of an essental molecule across the photoreceptor cell membrane. Mutations in this gene are found in patients diagnosed with Stargardt disease, a form of juvenile-onset macular degeneration. Mutations in this gene are also associated with retinitis pigmentosa-19, cone-rod dystrophy type 3, early-onset severe retinal dystrophy, fundus flavimaculatus, and macular degeneration age-related 2.
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Product Specification
Basic Information
Brands:Elabscience
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Place of Origin:China
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Shipping:The product is shipped with ice pack,upon receipt,store it immediately at the temperature recommended.
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Concentration:0.2 mg/mL
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Shelf Life:12 months
Storage:Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.
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Dilution:IHC 1:25-1:100
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Application:IHC
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Research Areas:Cancer;Neuroscience
Species Reactivity:Human
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Target Synonym:ABC 10;ABC A4;ABC transporter;retinal-specific;ABC10;ABCA 4;abcA4;ABCA4;ABCR;ARMD 2;ARMD2;ATP binding cassette 10;ATP binding cassette sub family A member 4;ATP binding cassette sub family A member4;ATP binding cassette transporter;ATP binding cassette transporter retinal specific;ATP binding cassette;sub family A (ABC1);member 4;ATP binding cassette;sub family A (ABC1);member4;ATP binding cassette10;ATP binding transporter;retina specific;ATP-binding cassette sub-family A member 4;CORD 3;CORD3;DKFZp781N1972;FFM;FLJ17534;Photoreceptor rim protein;Retina specific ABC transporter;Retinal specific ATP binding cassette transporter;Retinal-specific ATP-binding cassette transporter;RIM ABC transporter;RIM protein;RmP;RP 19;RP19;Stargardt disease protein;STGD;STGD1
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Buffer:PBS with 0.05% sodium azide and 50% glycerol, PH7.4
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Clonality:Polyclonal
Conjugation:Unconjugated
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