Elabscience

庫存單位: E-AB-53535_20μL-ES

ZNHIT3多株抗體，20 μL

ZNHIT3（鋅指，含有 HIT 型 3），也稱為 TRIP3（甲狀腺受體相互作用蛋白 3）或 HNF-4a 輔激活因子，是一種 155 個氨基酸蛋白質，含有一個 HIT 型鋅指並調節 PPAR 介導的脂肪細胞分化。 ZNHIT3 也共同活化 HNF-4，並且作為甲狀腺受體相互作用蛋白，ZNHIT3 與甲狀腺受體的配體結合域相互作用。編碼 ZNHIT3 的基因位於人類第 17 號染色體，佔人類基因組的 2.5% 以上，並編碼超過 1,200 個基因。兩個關鍵的腫瘤抑制基因與 17 號染色體有關，即 p53 和 BRCA1。 p53 表現的功能障礙或喪失與惡性細胞生長和李-法美尼症候群有關。與 p53 一樣，BRCA1 直接參與 DNA 修復，儘管它被公認為早發性乳腺癌和卵巢癌、結腸癌、前列腺癌和輸卵管癌的遺傳決定因素。

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Product Specification

Basic Information

Brands:Elabscience

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Place of Origin:中國

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Shipping:產品隨附冰袋，收到後，請立即在建議的溫度下存放。

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Concentration:2.4 毫克/毫升

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Shelf Life:12個月

Storage:儲存於-20°C，有效期限為12個月。避免凍融循環。

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Dilution:免疫組化 1:45-1:300

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Application:免疫組織化學

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Research Areas:表觀遺傳學和核子訊號；訊號傳導

Species Reactivity:人類

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Buffer:含 0.05% NaN3 和 40% 甘油的 PBS，pH7.4

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Conjugation:未結合

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