Elabscience

庫存單位: E-AB-18464_200μL-ES

ZNF354A多株抗體，200 μL

ZNF354A，也稱為 EZNF、KID-1 或​​ TCF17，屬於 Krüppel C2H2 型鋅指蛋白家族，含有 KRAB 結構域並充當轉錄調節劑。 ZNF354A 主要在成人腎臟中表達，是一種轉錄抑制因子，在晚期腎臟發育中發揮作用，並在腎臟缺血後受到抑制。 ZNF354A 的 N 端包含賦予轉錄阻遏活性的 KRAB 結構域，而 C 端則包含多個 Cys2His2-鋅指。 ZNF354A 位於核仁，被認為透過關閉可有可無或抑制基因來專門影響近端小管的發育。 ZNF354A 表達降低會阻止正常細胞分化，因此可能與腎癌有關。

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Product Specification

Basic Information

Brands:Elabscience

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Place of Origin:中國

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Shipping:產品隨附冰袋，收到後，請立即在建議的溫度下存放。

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Concentration:0.5毫克/毫升

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Shelf Life:12個月

Storage:儲存於-20°C，有效期限為12個月。避免凍融循環。

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Dilution:免疫組化 1:30-1:150

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Application:免疫組織化學

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Research Areas:表觀遺傳學和核子訊號；神經科學

Species Reactivity:人類;小鼠;大鼠

Reactivity:

Target Synonym:伊茲尼夫；香港L1；HLK1；智人鋅指蛋白354A；兒童1；孩子1；腎臟;缺血；及發育調節蛋白 1；腎臟轉錄因子 Kid 1 ； TCF-17；TCF17；轉錄因子 17；Z354A；鋅指蛋白354A；鋅指蛋白eZNFA；

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Buffer:含 0.05% NaN3 和 40% 甘油的 PBS，pH7.4

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Clonality:多克隆

Conjugation:未結合

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