Elabscience

庫存單位: E-AB-18321_200μL-ES

ZFAND5多株抗體，200 μL

透過泛素-蛋白酶體系統參與蛋白質降解。可能透過將泛素化蛋白質錨定到蛋白酶體上來發揮作用。在肌肉萎縮期間在泛素介導的蛋白質降解中發揮作用。在調節 NF-kappa-B 活化和細胞凋亡中發揮作用。抑制由 RIPK1 和 TRAF6 過度表現但不由 RELA 過度表現觸發的 NF-kappa-B 活化。也以劑量依賴性方式抑制腫瘤壞死因子 (TNF)、IL-1 和 TLR4 誘導的 NF-kappa-B 活化。過度表現使細胞對 TNF 誘導的細胞凋亡敏感。是破骨細胞分化的強效抑制因子。

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Product Specification

Basic Information

Brands:Elabscience

Model Number:

Place of Origin:中國

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Shipping:產品隨附冰袋，收到後，請立即在建議的溫度下存放。

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Concentration:1.4 毫克/毫升

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Calculated Molecular Weight:23千道爾頓

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Shelf Life:12個月

Storage:儲存於-20°C，有效期限為12個月。避免凍融循環。

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Calculated Molecular Weight:23千道爾頓

Dilution:免疫印跡法 1:500-1:2000；免疫組織化學法 1:25-1:100

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Application:免疫組化

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Research Areas:細胞生物學；表觀遺傳學和核子訊號；訊號傳導

Species Reactivity:人類;小鼠;大鼠

Reactivity:

Target Synonym:AN1型鋅指蛋白5；ZA20D2；ZFAN5；和5；ZFAND5A；含 2 個鋅指 A20 結構域；含鋅指A20結構域的蛋白2；含鋅指A20結構域的蛋白 2；鋅指AN1型結構域5；鋅指蛋白216；ZNF216；

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Buffer:含 0.05% NaN3 和 40% 甘油的 PBS，pH7.4

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Clonality:多克隆

Conjugation:未結合

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