Elabscience

庫存單位: E-AB-10661_20μL-ES

TPM1多株抗體，20 μL

該基因是原肌球蛋白家族的成員，該家族是高度保守、廣泛分佈的肌動蛋白結合蛋白，參與橫紋肌和平滑肌的收縮系統以及非肌肉細胞的細胞骨架。原肌球蛋白由兩條排列成捲曲螺旋狀的 α 螺旋鏈組成。它沿著肌動蛋白絲的兩個凹槽首尾相連地聚合，為肌動蛋白絲提供穩定性。編碼的蛋白質是一種 α 螺旋鏈，形成橫紋肌的主要原肌球蛋白，它也與肌鈣蛋白複合物一起發揮作用，調節肌肉收縮過程中肌動蛋白和肌球蛋白的鈣依賴性相互作用。在平滑肌細胞和非肌肉細胞中，編碼一系列異構體的剪接轉錄變體已被描述。此基因突變與第 3 型家族性肥厚型心肌病變有關。

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Product Specification

Basic Information

Brands:Elabscience

Model Number:

Place of Origin:中國

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Shipping:產品隨附冰袋，收到後，請立即在建議的溫度下存放。

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Concentration:0.1 毫克/毫升

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Calculated Molecular Weight:33kDa

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Shelf Life:12個月

Storage:儲存於-20°C，有效期限為12個月。避免凍融循環。

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Calculated Molecular Weight:33kDa

Dilution:免疫印跡法 1:500-1:2000

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Application:免疫組化

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Research Areas:癌症；心血管；訊號傳導

Species Reactivity:人類;小鼠;大鼠

Reactivity:

Target Synonym:AA986836；AI854628；Alpha 原肌球蛋白；alpha-TM；Alpha-原肌球蛋白；C15orf13；心肌病變；肥大性 3；CMD1Y；CMH3；HTM alpha；HTM-alpha；OTTHUMP00000163688； (alpha)；原肌球蛋白 1 (alpha) 異構體 1；原肌球蛋白 1 (alpha) 異構體 2；原肌球蛋白 1 (alpha) 異構體 3；原肌球蛋白 1 (alpha) 異構體 4；原肌球蛋白 1 (alpha) 異構體 5；原肌球蛋白 1 異構體 1； 7；原肌球蛋白 1；原肌球蛋白 α 1 鏈；原肌球蛋白 α-1 鏈；原肌球蛋白；骨骼肌 α；原肌球蛋白-1

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Buffer:含0.05%疊氮化鈉和50%甘油的PBS，PH7.4

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Clonality:多克隆

Conjugation:未結合

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