Elabscience

庫存單位: E-AB-22116_60μL-ES

TNF α單株抗體，60 μL

TNF，也稱為 TNF-alpha 或惡病質，是一種多功能促發炎細胞因子，屬於腫瘤壞死因子 (TNF) 超家族。它表達為 26 kDa 膜結合蛋白，然後被 TNF-alpha 轉換酶 (TACE) 裂解以釋放可溶性的 17 kDa 單體，該單體在循環中形成同型三聚體。它主要由活化的巨噬細胞產生，但它也可以由許多其他細胞類型產生，例如 CD4+ 淋巴細胞、NK 細胞、嗜中性球、肥大細胞、嗜酸性球和神經元。它可以與其受體 TNFRSF1A/TNFR1 和 TNFRSF1B/TNFBR 結合，並發揮作用。此細胞激素參與調節廣泛的生物過程，包括細胞增殖、分化、細胞凋亡、脂質代謝和凝血。這種細胞激素與多種疾病有關，包括自體免疫疾病、胰島素抗性和癌症。

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Product Specification

Basic Information

Brands:Elabscience

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Place of Origin:中國

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Shipping:產品隨附冰袋，收到後，請立即在建議的溫度下存放。

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Concentration:1毫克/毫升

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Observed Molecular Weight:17,25kDa

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Shelf Life:12個月

Storage:儲存於-20°C，有效期限為12個月。避免凍融循環。

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Dilution:白血球介素 1:1000-1:3000；免疫組織化學 1:50-1:200

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Application:WB;IHC-p

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Research Areas:癌症；心血管；代謝；免疫學；訊號傳導

Species Reactivity:人類;小鼠;大鼠

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Target Synonym:APC1；APC1 蛋白；惡病質；DIF；分化誘導因子；巨噬細胞細胞毒性因子；Tnf；TNF 超家族；成員 2；TNF；巨噬細胞衍生；TNF；單核細胞衍生；TNF-a；TNF-alpha；TNFA；TNFA；TNFSF2；腫瘤壞死因子 alphaphapha-a；TNF-alpha；TNFA；TNFA；TNFSF2；腫瘤壞死因子 alphaphaphapha-病毒；

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Buffer:含有 0.02% 疊氮化鈉和 50% 甘油的 PBS，pH 值為 7.4。

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Conjugation:未結合

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