Elabscience

庫存單位: E-AB-12901_60μL-ES

TERT 多株抗體，60 μL

端粒酶是一種核糖核蛋白聚合酶，透過添加端粒重複 TTAGGG 來維持端粒末端。該酶由該基因編碼的具有逆轉錄酶活性的蛋白質成分和作為端粒重複模板的 RNA 成分組成。端粒酶表現在細胞老化中起著重要作用，因為它通常在出生後的體細胞中受到抑制，導致端粒逐漸縮短。體細胞中端粒酶表現的失調可能與腫瘤發生有關。小鼠研究顯示端粒酶也參與染色體修復，因為端粒重複的從頭合成可能發生在雙股斷裂處。已經鑑定出編碼端粒酶逆轉錄酶不同亞型的剪接變體；一些變體的全長序列尚未確定。此基因位點的選擇性剪接被認為是調節端粒酶活性的機制。

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Product Specification

Basic Information

Brands:Elabscience

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Place of Origin:中國

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Shipping:產品隨附冰袋，收到後，請立即在建議的溫度下存放。

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Concentration:0.4 毫克/毫升

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Shelf Life:12個月

Storage:儲存於-20°C，有效期限為12個月。避免凍融循環。

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Dilution:免疫組化 1:50-1:200

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Application:免疫組織化學

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Research Areas:癌症；表觀遺傳學和核子訊號；發育生物學；幹細胞

Species Reactivity:人類

Reactivity:

Target Synonym:CMM9；DKCA2；DKCB4；EST2；HEST2；htert；hTRT；PFBMFT1；TCS1；端粒酶相關蛋白 2；端粒酶催化亞基；端粒酶逆轉錄酶；端粒酶相關蛋白 2；端粒逆轉錄酶；TERT；TERT；TP2；TRT逆轉錄酶；端粒酶相關蛋白 2；端粒逆轉錄酶；TERT；TERT；TP2；TRT

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Buffer:含0.05%疊氮化鈉和50%甘油的PBS，PH7.4

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