Elabscience

庫存單位: E-AB-52113_60μL-ES

SPI1多株抗體，60μL

SPI1 編碼 ETS 結構域轉錄因子，可在髓系和 B 淋巴細胞發育過程中活化基因表現。核蛋白與目標基因啟動子附近富含嘌呤的序列（稱為 PU-box）結合，並與其他轉錄因子和輔因子協調調節其表現。該蛋白質還可以調節目標基因的可變剪接。已發現該基因有多種編碼不同異構體的轉錄變異。 SPI1（Spi-1 原癌基因）是一種蛋白質編碼基因。與SPI1相關的疾病包括發炎性腹瀉和交錯樹突狀細胞肉瘤。其相關路徑包括 C-MYC 轉錄抑制和 C-MYB 轉錄因子網絡的已驗證標靶。與此基因相關的GO註釋包括轉錄因子活性、序列特異性DNA結合和RNA結合。該基因的一個重要的旁系同源物是SPIB。

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Product Specification

Basic Information

Brands:Elabscience

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Place of Origin:中國

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Shipping:產品隨附冰袋，收到後，請立即在建議的溫度下存放。

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Calculated Molecular Weight:31千道爾頓

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Shelf Life:12個月

Storage:儲存於-20°C，有效期限為12個月。避免凍融循環。

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Calculated Molecular Weight:31千道爾頓

Dilution:寬螢幕 1:500-1:2000

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Application:世界銀行

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Research Areas:癌症；表觀遺傳學和核子訊號；免疫學

Species Reactivity:人類;小鼠;大鼠

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Target Synonym:轉錄因子 spi1；31 kDa 轉殖蛋白；31 kDa 轉殖蛋白；cb1086；造血轉錄因子 PU.1；OF；致癌基因 spi1；PU.1；SFFV 病毒誘發的鼠紅白血病致癌基因；小鼠；同源物；SFPI1；si:by184l24.2；SPI 1PI；小鼠；同種 SFFAPI；病毒整合致癌基因 spi1；脾臟病灶形成病毒原病毒整合致癌基因 spi1；轉錄因子 PU.1

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Buffer:含 0.05% NaN3 和 40% 甘油的 PBS，pH7.4

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