Elabscience

庫存單位: E-AB-15382_120μL-ES

SEMA4A 多株抗體，120 μL

該基因編碼訊號蛋白家族的一個成員，該家族屬於可溶性跨膜蛋白。訊號蛋白參與多種功能，包括軸突引導、形態發生、致癌作用和免疫調節。編碼的蛋白質是單程I型膜蛋白，含有免疫球蛋白樣C2型結構域、PSI結構域和sema結構域。它透過提供局部訊號來指定生長軸突無法進入的區域，從而抑制軸突延伸。它是 T 細胞介導免疫的活化劑，可抑制血管內皮生長因子 (VEGF) 介導的體外內皮細胞遷移和增殖以及體內血管生成。此基因突變與視網膜退化性疾病有關，包括視網膜色素變性 35 型 (RP35) 和視錐桿營養不良 10 型 (CORD10)。已經鑑定出多種編碼不同亞型的剪接轉錄變異體。

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Product Specification

Basic Information

Brands:Elabscience

Model Number:

Place of Origin:中國

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Shipping:產品隨附冰袋，收到後，請立即在建議的溫度下存放。

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Concentration:0.8 毫克/毫升

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Shelf Life:12個月

Storage:儲存於-20°C，有效期限為12個月。避免凍融循環。

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Dilution:免疫組化 1:30-1:150

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Application:免疫組織化學

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Research Areas:癌症；心血管；神經科學

Species Reactivity:人類

Reactivity:

Target Synonym:CORD10；RP11 54H19 2；RP35；SEM4A；Sema B；Sema 結構域免疫球蛋白結構域 Ig 跨膜結構域 TM 和短胞質結構域 4A；Sema 結構域免疫球蛋白結構域 Ig 跨膜結構域 TM 和短胞質結構域 semaphorin 4A4emaphorin (4A4ema)； a；SEMAB；Semaphorin 4A 前驅物；Semaphorin B；Semaphorin-4A；Semaphorin-B；SEMB

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Buffer:含0.05%疊氮化鈉和50%甘油的PBS，PH7.4

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Conjugation:未結合

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