Elabscience

庫存單位: E-AB-15491_60μL-ES

RHOA多株抗體，60 μL

調節連接質膜受體與黏著斑和肌動蛋白應力纖維組裝的訊號傳導路徑。參與細胞週期胞質分裂過程中肌球蛋白收縮環形成所需的微管依賴性訊號。在裂隙的形成中起著至關重要的作用。角質形成細胞與細胞間黏附的頂端連接形成所需。作為鼠疫媒介耶爾森氏菌和導致胃腸道疾病的耶爾森氏菌的 yopT 半胱氨酸勝肽酶的標靶。刺激 PKN2 激酶活性。可能是 PLCE1 的活化劑。由ARHGEF2激活，促進GDP與GTP的交換。對於 SPATA13 介導的細胞遷移和黏附組裝和拆卸的調節至關重要。 MEMO1-RHOA-DIAPH1訊息傳遞路徑在ERBB2依賴的細胞皮層微管穩定中扮演重要角色。它透過調節 GSK3B 活性來控制 APC 和 CLASP2 到細胞膜的定位。反過來，膜結合 APC 允許 MACF1 定位到細胞膜，這對於微管捕獲和穩定性是必要的。

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Product Specification

Basic Information

Brands:Elabscience

Model Number:

Place of Origin:中國

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Shipping:產品隨附冰袋，收到後，請立即在建議的溫度下存放。

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Concentration:0.2毫克/毫升

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Calculated Molecular Weight:22kDa

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Shelf Life:12個月

Storage:儲存於-20°C，有效期限為12個月。避免凍融循環。

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Calculated Molecular Weight:22kDa

Dilution:寬螢幕 1:500-1:2000

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Application:世界銀行

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Research Areas:癌症；訊號傳導

Species Reactivity:人類;小鼠;大鼠

Reactivity:

Target Synonym:海兔 ras 相關同源物 12;ARH12;ARHA;H 12;H12;致癌基因 RHO H12;Ras 同源物家族成員 A;Ras 同源物基因家族成員 A;Rho A;Rho cDNA 克隆 ​​12;RHO H12;RHO12;Rho A;Rho cDNA 克隆 ​​12;RHO H12;RHO12;Rho A;Rho cDNA 克隆 ​​12;RHO H12;RHO12;RHOA;RHOA;RHOA.

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Buffer:含0.05%疊氮化鈉和50%甘油的PBS，PH7.4

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Clonality:多克隆

Conjugation:未結合

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