庫存單位: PKSM040305_50μg-ES

重組小鼠 SRC 激酶/c-SRC 蛋白 (His & GST 標籤), 50 μg

原癌基因酪胺酸蛋白激酶SRC是一種疏水性蛋白,屬於SRC家族激酶,該家族包含9個成員,屬於非受體酪胺酸激酶家族。 SRC蛋白可能以不同的形式存在:C-SRC和V-SRC。 C-SRC 僅在某些情況下被激活,例如生長因子訊號傳導,而 V-SRC 與正常 SRC(C-SRC)相比,是一種組成性活性物質。因此,V-SRC 是致癌基因蛋白激酶的典型例子,而 C-SRC 是原癌基因蛋白激酶。透過 PSD-95 介導的 NR2A 酪胺酸磷酸化抑制 SRC 可能有助於鋰誘導的 NMDA 受體功能下調並提供對興奮毒性的神經保護。

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Product Specification

Basic Information

Brands:Elabscience

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Place of Origin:中國

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Reconstitution:不適用

Shipping:本產品以液體形式提供。它是在冷凍溫度下用藍冰/凝膠包運輸的。收到後,立即存放在<-20°C的環境中。

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Calculated Molecular Weight:87.7 kDa

Observed Molecular Weight:80千道爾頓

Purity: 以還原 SDS-PAGE 測定,結果為 > 90%。

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Storage:儲存溫度<-20°C,可穩定保存6個月。請盡量減少凍融循環。

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Calculated Molecular Weight:87.7 kDa

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Endotoxin: 經 LAL 方法測定,每 μg 蛋白質含量 < 1.0 EU。

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Application:酵素

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Bio-activity:使用聚[Glu,Tyr]4:1作為底物,測定比活性為> 80 nmol/min/mg。

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Formulation:以 20mM Tris、500mM NaCl、10% 甘油、pH 8.0 的無菌溶液形式提供

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