Elabscience

庫存單位: PKSM041335_50μg-ES

重組小鼠 SerpinE2/SERPINE2 蛋白 (His 標籤), 50 μg

Serpin E2 是絲胺酸蛋白酶抑制劑 Serpin 超家族的成員。絲胺酸蛋白酶抑制劑 E2 是凝血酶、纖溶酶和纖溶酶原激活劑的強效抑制劑。它在神經元分化過程中表現出差異表達，並且能夠將人類胚胎腎細胞轉化為神經元樣細胞。其在小鼠體內的過度表現導致這些動物出現進行性神經元和運動功能障礙。它在大多數胰臟癌以及胃癌和結直腸癌樣本中也過度表達，而在所有正常胰臟和慢性胰臟炎組織樣本中均弱表達。它在控制男性生育能力方面發揮著重要作用，因為其基因敲除的雄性小鼠從性成熟開始就表現出明顯的生育能力受損，並且在患有精子功能障礙的男性的精液中也發現了其異常表達。

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Product Specification

Basic Information

Brands:Elabscience

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Place of Origin:中國

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Reconstitution:不適用

Shipping:本產品以液體形式提供。它是在冷凍溫度下用藍冰/凝膠包運輸的。收到後，立即存放在<-20°C的環境中。

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Calculated Molecular Weight:43.2 kDa

Observed Molecular Weight:50-55kDa

Purity: 以還原 SDS-PAGE 測定，結果 > 95%。

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Storage:儲存溫度<-20°C，可穩定保存6個月。請盡量減少凍融循環。

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Calculated Molecular Weight:43.2 kDa

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Endotoxin: 經 LAL 方法測定，每 μg 蛋白質含量 < 1.0 EU。

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Bio-activity:未驗證活動

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Formulation:以 0.2 μm 過濾溶液的形式提供，其中含有 20mM 乙酸鈉、150 mM NaCl、5% 海藻糖、5% 甘露醇、0.02% Tween 80、1mM EDTA、pH 4.0。

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