庫存單位: PKSM041478_20μg-ES

重組小鼠IL-11蛋白(His標籤),20 μg

白血球介素-11(IL-11)是一種分泌蛋白,屬於IL-6超家族。 IL-11 已被證明能改善化療引起的血小板減少症後的血小板恢復,誘導急性期蛋白,調節抗原抗體反應,參與調節骨細胞增殖和分化,並可作為骨質疏鬆症的治療藥物。 IL-11 刺激某些淋巴球的生長,在小鼠模型中,刺激長骨皮質厚度和強度的增加。除了具有淋巴細胞生成/造血和成骨特性外,它還在許多其他組織中發揮作用,包括大腦、腸道、睪丸和骨骼。

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Product Specification

Basic Information

Brands:Elabscience

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Place of Origin:中國

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Reconstitution:請參閱印刷手冊以取得詳細資訊。

Shipping:本產品以凍乾粉形式提供,並附冰袋運送。

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Calculated Molecular Weight:20.0 千道爾頓

Observed Molecular Weight:17-25kDa

Purity: 以還原 SDS-PAGE 測定,結果為 > 98%。

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Storage:一般來說,冷凍乾燥蛋白在-20至-80℃保存可穩定保存長達12個月。重建後的蛋白溶液可在4-8℃保存2-7天。重建樣品的等分試樣在 < -20℃ 穩定保存 3 個月。

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Calculated Molecular Weight:20.0 千道爾頓

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Endotoxin: 依照 LAL 方法測定,每 μg 蛋白質含量 < 0.1 EU。

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Features and Capabilities

Application:細胞培養

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Bio-activity:透過其誘導T11細胞增殖的能力來衡量。此效果的ED 50為<0.5 ng/mL。重組小鼠IL-11的比活性為> 2 x 10 6 IU/mg。

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Formulation:從無菌 PBS 冷凍乾燥,pH 值為 8.0。
通常在冷凍乾燥前會添加5%~8%的海藻糖、甘露醇和0.01%的吐溫80作為保護劑。
請參閱印刷手冊中的具體緩衝液資訊。

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