Elabscience

庫存單位: PKSM041057_10μg-ES

重組小鼠IDO1/IDO蛋白（His標籤），10 μg

吲哚胺 2,3-雙加氧酶 (IDO) 是一種血紅素酶，它沿著犬尿氨酸途徑啟動最不豐富的必需氨基酸 l-色氨酸的氧化降解。這種蛋白質通常在樹突狀細胞、巨噬細胞、小膠質細胞、嗜酸性粒細胞、纖維母細胞、內皮細胞和大多數腫瘤細胞中表現。 IDO活性與免疫抑制和免疫衰減有關。多項研究表明，當IDO直接在腫瘤細胞中表達或在免疫抑制抗原呈現細胞（如耐受性樹突狀細胞或腫瘤相關巨噬細胞）中表達時，IDO可導致免疫逃脫。 IDO也是治療癌症、慢性病毒感染和其他以病理性免疫抑制為特徵的疾病的有希望的治療標靶。

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Product Specification

Basic Information

Brands:Elabscience

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Place of Origin:中國

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Reconstitution:不適用

Shipping:本產品以液體形式提供。它是在冷凍溫度下用藍冰/凝膠包運輸的。收到後，立即存放在<-20°C的環境中。

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Calculated Molecular Weight:47.1 kDa

Observed Molecular Weight:40-50kDa

Purity: 以還原 SDS-PAGE 測定，結果 > 95%。

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Storage:儲存溫度<-20°C，可穩定保存6個月。請盡量減少凍融循環。

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Calculated Molecular Weight:47.1 kDa

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Endotoxin: 經 LAL 方法測定，每 μg 蛋白質含量 < 1.0 EU。

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Bio-activity:未驗證活動

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Formulation:以 0.2 μm 過濾溶液的形式提供，其中包含 20mM Tris-HCl、500mM NaCl、0.01% Tween 80、1mM EDTA、50% 甘油，pH 8.0。

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