Elabscience

庫存單位: PKSM041229_10μg-ES

重組小鼠 DR6/TNFRSF21 蛋白 (His 標籤), 10 μg

腫瘤壞死因子受體超家族成員 21（DR6）是單程 I 型膜蛋白，含有 1 個死亡結構域和 4 個 TNFR-Cys 重複序列。該蛋白質可能會活化 NF-kappa-B 並促進細胞凋亡，它可能會活化 JNK 並參與 T 細胞分化。它是正常細胞體死亡和軸突修剪所必需的。營養因子缺乏會觸發 β-分泌酶裂解表面 APP，釋放 sAPP-β，sAPP-β 進一步裂解釋放 APP 的 N 端片段 (N-APP)。 N-APP 結合 TNFRSF21 觸發 caspase 活化以及神經元胞體（透過 caspase-3）和軸突（透過 caspase-6）的退化。

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Product Specification

Basic Information

Brands:Elabscience

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Place of Origin:中國

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Reconstitution:請參閱印刷手冊以取得詳細資訊。

Shipping:本產品以凍乾粉形式提供，並附冰袋運送。

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Calculated Molecular Weight:64.7 kDa

Observed Molecular Weight:75-120千道爾頓

Purity: 以還原 SDS-PAGE 測定，結果 > 95%。

Shelf Life:

Storage:一般來說，冷凍乾燥蛋白在-20至-80℃保存可穩定保存長達12個月。重建後的蛋白溶液可在4-8℃保存2-7天。重建樣品的等分試樣在 < -20℃ 穩定保存 3 個月。

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Calculated Molecular Weight:64.7 kDa

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Endotoxin: 經 LAL 方法測定，每 μg 蛋白質含量 < 1.0 EU。

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Research Areas:細胞生物學

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Bio-activity:未驗證活動

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Formulation:從 0.2 μm 過濾的 PBS 溶液（pH 7.4）中冷凍乾燥。
通常在冷凍乾燥前會添加5%～8%的海藻糖、甘露醇和0.01%的吐溫80作為保護劑。
請參閱印刷手冊中的具體緩衝液資訊。

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