Elabscience

庫存單位: PKSM040963_10μg-ES

重組小鼠 ANGPTL4 蛋白（Fc 標籤），10 μg

血管生成素相關蛋白 4（ANGPTL4）是一種分泌蛋白，含有 1 個纖維蛋白原 C 端結構域。該蛋白質可能充當血管生成調節劑並調節腫瘤發生。它抑制內皮細胞的增殖、遷移和小管形成，並減少血管滲漏。 ANGPTL4可能透過內分泌作用對內皮細胞發揮保護作用。它直接參與調節葡萄糖穩態、脂質代謝和胰島素敏感性（透過相似性）。為了應對缺氧，未加工形式的蛋白質會在內皮下細胞外基質 (ECM) 中累積。基質相關和固定的未處理形式限制了黏附內皮細胞中肌動蛋白應力纖維和局部接觸的形成並抑制了它們的黏附。它還會降低內皮細胞的運動能力並抑制發芽和管道形成。

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Product Specification

Basic Information

Brands:Elabscience

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Place of Origin:中國

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Reconstitution:不適用

Shipping:本產品以液體形式提供。它是在冷凍溫度下用藍冰/凝膠包運輸的。收到後，立即存放在<-20°C的環境中。

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Calculated Molecular Weight:54.6 kDa

Observed Molecular Weight:67 千道爾頓

Purity: 以還原 SDS-PAGE 測定，結果 > 95%。

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Storage:儲存溫度<-20°C，可穩定保存6個月。請盡量減少凍融循環。

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Calculated Molecular Weight:54.6 kDa

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Endotoxin: 經 LAL 方法測定，每 μg 蛋白質含量 < 1.0 EU。

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Formulation:以 0.2 μm PBS 過濾溶液（pH7.4）提供。

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