庫存單位: PKSM040960_10μg-ES

重組小鼠脂聯素/AdipoQ 蛋白(大腸桿菌,His 標籤),10 μg

脂聯素是一種分泌蛋白。它僅由脂肪細胞合成並分泌到血漿中。脂聯素是一種重要的脂肪因子,參與控制脂肪代謝和胰島素敏感性,具有直接的抗糖尿病、抗動脈粥狀硬化和抗發炎作用。脂聯素刺激 AMPK 磷酸化並在肝臟和骨骼肌中激活,增強葡萄糖利用和脂肪酸燃燒。脂聯素也透過負向調節TNF-alpha在肝臟和巨噬細胞等各種組織中的表現以及抵消其作用來拮抗TNF-alpha。它透過 cAMP 依賴性途徑抑制內皮 NF-kappa-B 訊號傳導。脂聯素可能透過結合和隔離具有不同結合親和力的各種生長因子在細胞生長、血管生成和組織重塑中發揮作用,具體取決於複合物的類型:LMW、MMW 或 HMW。

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Product Specification

Basic Information

Brands:Elabscience

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Place of Origin:中國

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Reconstitution:請參閱印刷手冊以取得詳細資訊。

Shipping:本產品以凍乾粉形式提供,並附冰袋運送。

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Calculated Molecular Weight:27.2 kDa

Observed Molecular Weight:30千道爾頓

Purity: 以還原 SDS-PAGE 測定,結果為 > 90%。

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Storage:一般來說,冷凍乾燥蛋白在-20至-80℃保存可穩定保存長達12個月。重建後的蛋白溶液可在4-8℃保存2-7天。重建樣品的等分試樣在 < -20℃ 穩定保存 3 個月。

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Calculated Molecular Weight:27.2 kDa

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Endotoxin: 經 LAL 方法測定,每 μg 蛋白質含量 < 1.0 EU。

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Bio-activity:未驗證活動

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Formulation:從 0.2 μm 過濾的 PBS 溶液(pH 7.4)中冷凍乾燥。
通常在冷凍乾燥前會添加5%~8%的海藻糖、甘露醇和0.01%的吐溫80作為保護劑。
請參閱印刷手冊中的具體緩衝液資訊。

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