Elabscience

庫存單位: E-AB-81430_50μL-ES

重組IKB alpha單株抗體，50 μL

B細胞抑制劑α中的κ輕多勝肽基因增強子的核因子（NFKBIA，同義詞：IKBA、MAD-3、NFKBI）。 NFKB1 或 NFKB2 與 REL、RELA 或 RELB 結合形成 NFKB 複合物。 NFKB 複合物被 I-κ-B 蛋白 (NFKBIA 或 NFKBIB) 抑制，後者透過將 NF-κ-B 捕獲在細胞質中而使其失去活性。激酶 (IKBKA 或 IKBKB) 對 I-κ-B 蛋白上的絲胺酸殘基進行磷酸化，進而透過泛素化途徑將其破壞，活化 NF-κ-B 複合物。活化的 NFKB 複合物轉位到細胞核中，並在 kappa-B 結合基序（例如 5-prime GGGRNNYYCC 3-prime 或 5-prime HGGARNYYCC 3-prime）處與 DNA 結合。

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Product Specification

Basic Information

Brands:Elabscience

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Place of Origin:中國

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Shipping:產品隨附冰袋，收到後，請立即在建議的溫度下存放。

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Concentration:300微克/毫升

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Calculated Molecular Weight:36kDa

Observed Molecular Weight:39kDa

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Shelf Life:12個月

Storage:儲存於-20°C，有效期限為12個月。避免凍融循環。

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Calculated Molecular Weight:36kDa

Dilution:廣西 1:1000-1:2000

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Application:世界銀行

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Research Areas:癌症;表觀遺傳學和核子訊號傳導；免疫學；訊號傳導

Species Reactivity:人類;鼠

Reactivity:

Target Synonym:I kappa B α;I-kappa-B-α;IkappaBα;IkB-α;IKBA;IKBA;IKBα;MAD 3;MAD3;NF kappa B 抑制劑 α;NFKBI;IKB α

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Buffer:50mM Tris-Glycine（pH 7.4）、0.15M NaCl、40% 甘油、0.01% 疊氮化鈉和 0.05% 保護蛋白

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Clonality:兔單克隆

Conjugation:未結合

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