Elabscience

庫存單位: PKSH032744_10μg-ES

重組人 VAP-1/AOC3 蛋白 (His 標籤), 10 μg

血管黏附蛋白-1（VAP-1）是一種具有托帕醌輔因子的銅胺氧化酶。 VAP-1 是一種 II 型整合膜蛋白；但人類血清中存在這種酵素的可溶形式；在糖尿病和某些發炎性肝病中其水平會升高。 VAP-1催化甲胺等小分子一級胺的氧化脫氨作用；芐胺；與氨基丙酮反應生成醛；氨;和 H2O2。 VAP-1 血管表現在發炎部位受到調節，透過從儲存該蛋白質的細胞內顆粒中釋放出來。研究顯示 VAP-1 的黏附功能，該蛋白質對於某些淋巴細胞亞型黏附於發炎內皮組織很重要。 VAP-1介導的黏附參與了白血球外滲的過程；發炎反應的重要特徵。 VAP-1被認為是糖尿病的治療標靶；氧化壓力；和發炎性疾病。

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Product Specification

Basic Information

Brands:Elabscience

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Place of Origin:中國

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Reconstitution:不適用

Shipping:本產品以液體形式提供。它是在冷凍溫度下用藍冰/凝膠包運輸的。收到後，立即存放在<-20°C的環境中。

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Calculated Molecular Weight:82.6 kDa

Observed Molecular Weight:90-110 kDa

Purity: 以還原 SDS-PAGE 測定，結果 > 95%。

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Storage:儲存溫度<-20°C，可穩定保存6個月。請盡量減少凍融循環。

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Calculated Molecular Weight:82.6 kDa

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Endotoxin: 經 LAL 方法測定，每 μg 蛋白質含量 < 1.0 EU。

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Research Areas:訊號傳導；神經科學；

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Bio-activity:未驗證活動

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Formulation:以 20mM Tris-HCl、500mM NaCl、pH 8.0 的 0.2 μm 過濾溶液形式提供。

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