庫存單位: PDMH100427_100μg-ES

重組人尿激酶/uPA 蛋白(His 標籤),100 μg

重組人尿激酶型纖溶酶原激活劑是一種絲氨酸蛋白酶,它特異性地裂解酶原纖溶酶原,形成活性酶纖溶酶。尿激酶型纖溶酶原激活劑是與乳癌、結腸癌、胃癌、膀胱癌、腦癌、卵巢癌和子宮內膜癌相關的多種人類癌症侵襲和轉移的有效標記。人類尿激酶型纖溶酶原激活劑最初合成為具有N端信號肽殘基的431個氨基酸前體。單鏈分子被加工成二硫鍵連接的雙鏈分子。 A 鏈有兩種形式,長 A 鏈含有負責與 uPA 受體結合的 EGF 樣結構域。 B鏈對應於催化域。

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Product Specification

Basic Information

Brands:Elabscience

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Place of Origin:中國

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Reconstitution:建議將無菌水加入小瓶中,配製 0.5 mg/mL 的儲備溶液。濃度透過紫外可見光測量。

Shipping:本產品以凍乾粉形式提供,並附冰袋運送。

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Calculated Molecular Weight:47.3 kDa

Observed Molecular Weight:45千道爾頓

Purity: 以還原 SDS-PAGE 測定,結果 > 95%。

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Storage:一般來說,冷凍乾燥蛋白在-20至-80℃保存可穩定保存長達12個月。重建後的蛋白溶液可在4-8℃保存2-7天。重建樣品的等分試樣在 < -20℃ 穩定保存 3 個月。

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Calculated Molecular Weight:47.3 kDa

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Endotoxin:經 LAL 方法測定,蛋白質含量 < 1.0 EU/mg。

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Research Areas:心血管;神經科學;癌症;代謝

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Bio-activity:未驗證活動

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Formulation:由無菌 PBS 冷凍乾燥而成,pH 值為 7.4。
通常在冷凍乾燥前添加5%-8%的海藻糖、甘露醇和0.01%的吐溫80作為保護劑。
請參閱印刷手冊中的具體緩衝液資訊。

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