Elabscience

庫存單位: PKSH033539_10μg-ES

重組人類 RNASET2 蛋白（人類細胞，His 標籤），10 μg

RNASET2（核糖核酸酶 T2）是一種屬於 RNase T2 家族的酵素。它在顳葉和胎兒大腦中高度表達。 RNASET2 基因是細胞外核糖核酸酶 Rh/T2/S-醣蛋白類的新成員。該蛋白質可以被 Zn2+ 和 Cu2+ 抑制。它具有核糖核酸酶活性，在酸性pH下活性較高，可能參與核醣體RNA的溶小體降解。 RNASET2 缺陷是導致不伴隨巨腦症的囊性白質腦病變的原因。一種嬰兒期發病的腦白質腦病變症候群。受影響的新生兒會出現小頭畸形和神經系統異常，包括精神運動障礙、癲癇和感音神經性聽力障礙。腦部可見多灶性白質病變、前顳葉皮質下囊腫、囊週異常髓鞘形成、腦室擴大及顱內鈣化。

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Product Specification

Basic Information

Brands:Elabscience

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Place of Origin:中國

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Reconstitution:不適用

Shipping:本產品以液體形式提供。它是在冷凍溫度下用藍冰/凝膠包運輸的。收到後，立即存放在<-20°C的環境中。

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Calculated Molecular Weight:28.2 kDa

Observed Molecular Weight:38-45kDa

Purity: 以還原 SDS-PAGE 測定，結果 > 95%。

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Storage:儲存溫度<-20°C，可穩定保存6個月。請盡量減少凍融循環。

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Calculated Molecular Weight:28.2 kDa

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Endotoxin: 經 LAL 方法測定，每 μg 蛋白質含量 < 1.0 EU。

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Research Areas:癌症；表觀遺傳學和核子訊號

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Bio-activity:未驗證活動

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Formulation:以 0.2 μm 過濾溶液的形式提供，其中含有 20mM Tris-HCl、150mM NaCl、20% 甘油，pH 7.5。

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