Elabscience

庫存單位: PKSH032984_10μg-ES

重組人 PKLR 蛋白 (His 標籤), 10 μg

丙酮酸激酶同功酶R/L（PKLR）屬於丙酮酸激酶家族，哺乳動物有4種丙酮酸激酶同功酶：L、R、M1和M2。 L型是肝臟中主要的同工酶； R 存在於紅血球中； M1是肌肉、心臟和腦中的主要形式； M2 存在於早期胎兒組織中。 PKLR 以同型四聚體的形式存在，能催化丙酮酸和 ATP 生成磷酸烯醇式丙酮酸。 PKLR 缺陷也是紅血球丙酮酸激酶缺乏的原因，而紅血球丙酮酸激酶缺乏是遺傳性非球形紅血球溶血性貧血的常見原因。

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Product Specification

Basic Information

Brands:Elabscience

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Place of Origin:中國

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Reconstitution:不適用

Shipping:本產品以液體形式提供。它是在冷凍溫度下用藍冰/凝膠包運輸的。收到後，立即存放在<-20°C的環境中。

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Calculated Molecular Weight:62.9 kDa

Observed Molecular Weight:58千道爾頓

Purity: 以還原 SDS-PAGE 測定，結果 > 95%。

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Storage:儲存溫度<-20°C，可穩定保存6個月。請盡量減少凍融循環。

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Calculated Molecular Weight:62.9 kDa

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Endotoxin: 經 LAL 方法測定，每 μg 蛋白質含量 < 1.0 EU。

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Research Areas:訊號傳導；心血管；癌症；表觀遺傳學和核子訊號；代謝；

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Bio-activity:未驗證活動

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Formulation:以 0.2 μm 過濾溶液的形式提供，其中包含 20mM Tris-HCl、500mM NaCl、5% 海藻糖、5% 甘露醇、0.02% Tween 80、50% 甘油、1mM EDTA、1mM DTT、pH8.0。

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