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庫存單位: PKSH032028_50μg-ES
重組人 HPD/4HPPD 蛋白（His 標籤），50 μg
4-羥基苯丙酮酸雙加氧酶（4HPPD）屬於4HPPD家族。 4HPPD是酪胺酸降解過程中的關鍵酶，催化酪胺酸分解代謝的第二個反應即4-羥基苯丙酮酸轉化為尿黑酸。 4HPPD以同型二聚體形式存在，它利用鋅作為輔因子催化L-苯丙胺酸轉化為富馬酸和乙醯乙酸的第三步驟。當人體內活性4HPPD酶濃度較低時，就會導致血液中酪胺酸濃度過高，造成出生時輕度智力障礙，並隨著患者年齡增長導致視力下降。
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Product Specification
Basic Information
Brands:Elabscience
Model Number:
Place of Origin:中國
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Reconstitution:不適用
Shipping:本產品以液體形式提供。它是在冷凍溫度下用藍冰/凝膠包運輸的。收到後，立即存放在<-20°C的環境中。
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Calculated Molecular Weight:47.1 kDa
Observed Molecular Weight:40-50kDa
Purity: 以還原 SDS-PAGE 測定，結果 > 95%。
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Storage:儲存溫度<-20°C，可穩定保存6個月。請盡量減少凍融循環。
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Calculated Molecular Weight:47.1 kDa
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Endotoxin: 經 LAL 方法測定，每 μg 蛋白質含量 < 1.0 EU。
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Research Areas:訊號傳導；細胞生物學；代謝；
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Bio-activity:未驗證活動
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Formulation:以 0.2 μm 過濾溶液的形式提供，其中含有 20mM Tris-HCl、50mM NaCl、1mM DTT、20% 甘油，pH 8.0。
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