庫存單位: PKSH034036_10μg-ES

重組人 HLA-A*0201 NY-ESO-1 複合蛋白 (C-10His),10 μg

NY-ESO-1 是一種眾所周知的癌症睪丸抗原 (CTA),在多種癌症類型中重新表達。它能夠引發自發性的體液和細胞免疫反應,再加上其受限的表達模式,使其成為癌症免疫治療的良好候選標靶。最佳組裝的勝肽-HLA-B2M三聚體轉移到抗原呈現細胞表面,在那裡與T細胞表面的TCR和CD8共受體相互作用。

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Product Specification

Basic Information

Brands:Elabscience

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Place of Origin:中國

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Reconstitution:請參閱印刷手冊以取得詳細資訊。

Shipping:本產品以凍乾粉形式提供,並附冰袋運送。

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Calculated Molecular Weight:49.1 kDa

Observed Molecular Weight:55-60kDa

Purity: 以還原 SDS-PAGE 測定,結果為 > 90%。

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Storage:一般來說,冷凍乾燥蛋白在-20至-80℃保存可穩定保存長達12個月。重建後的蛋白溶液可在4-8℃保存2-7天。重建樣品的等分試樣在 < -20℃ 穩定保存 3 個月。

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Calculated Molecular Weight:49.1 kDa

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Endotoxin: 經 LAL 方法測定,每 μg 蛋白質含量 < 1.0 EU。

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Research Areas:微生物學;免疫學;心血管;癌症

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Bio-activity:未驗證活動

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Formulation:從 20mM PB、500mM NaCl、pH7.4 的 0.2 μm 過濾溶液中冷凍乾燥。
通常在冷凍乾燥前會添加5%~8%的海藻糖、甘露醇和0.01%的吐溫80作為保護劑。
請參閱印刷手冊中的具體緩衝液資訊。

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