Elabscience

庫存單位: PKSH030418_50μg-ES

重組人 EphB4/HTK 蛋白 (aa 563-987, His & GST 標籤), 50 μg

Ephrin B 型受體 4 是一種在人類中由 EPHB4 基因編碼的蛋白質。它是一種單程 I 型膜蛋白，屬於蛋白激酶超家族的 Ephrin 受體亞家族。 Ephrin 和 Eph 家族的成員是細胞功能的局部介質，透過發育和成熟過程中很大程度上依賴接觸的過程進行。此外，EphB4蛋白和相應的配體Ephrin-B2有助於各種人類腫瘤的生長。 EphB4蛋白具有腫瘤抑制活性，調節細胞增殖、細胞外基質重塑和侵襲潛力是腫瘤抑制的重要機制。因此，Ephrin-B2/EphB4 可能被視為癌症的新型預後指標。

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Product Specification

Basic Information

Brands:Elabscience

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Place of Origin:中國

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Reconstitution:不適用

Shipping:本產品以液體形式提供。它是在冷凍溫度下用藍冰/凝膠包運輸的。收到後，立即存放在<-20°C的環境中。

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Calculated Molecular Weight:75.2 kDa

Observed Molecular Weight:66千道爾頓

Purity: 以還原 SDS-PAGE 測定，結果為 > 90%。

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Storage:儲存溫度<-20°C，可穩定保存6個月。請盡量減少凍融循環。

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Calculated Molecular Weight:75.2 kDa

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Endotoxin: 經 LAL 方法測定，每 μg 蛋白質含量 < 1.0 EU。

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Application:酵素

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Research Areas:訊號傳導；心血管；神經科學；癌症；幹細胞

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Bio-activity:使用聚（Glu：Tyr）4：1作為底物，測定比活性為47 nmol/min/mg。

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Formulation:以 20mM Tris、500mM NaCl、pH 8.0、3mM DTT、10% 甘油的無菌溶液形式提供

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