Elabscience

庫存單位: PKSH032379_50μg-ES

重組人 Endoglin/CD105 蛋白 (His&Trx 標籤), 50 μg

Endoglin 是一種單程 I 型膜蛋白，僅限於除骨髓外所有組織的內皮細胞。 Endoglin是血管內皮的主要糖蛋白，存在於內皮細胞、活化巨噬細胞、纖維母細胞和平滑肌細胞中。此外，同型二聚體與轉化生長因子-β的訊號受體：TGFBR1 和/或 TGFBR2 形成異聚複合物。它可能在內皮細胞與整合素和/或其他 RGD 受體的結合中發揮重要作用。 ENG 缺陷是遺傳性出血性毛細血管擴張症 1 型 (HHT1) 的病因，該疾病是一種常染色體顯性多系統血管發育不良，其特徵是複發性鼻出血、黏膜皮膚毛細血管擴張、胃腸道出血以及肺部 (PAVM)、腦 (CAVM) 和肝動靜脈畸形。

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Product Specification

Basic Information

Brands:Elabscience

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Place of Origin:中國

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Reconstitution:不適用

Shipping:本產品以液體形式提供。它是在冷凍溫度下用藍冰/凝膠包運輸的。收到後，立即存放在<-20°C的環境中。

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Calculated Molecular Weight:33.6 kDa

Observed Molecular Weight:34千道爾頓

Purity: 以還原 SDS-PAGE 測定，結果 > 95%。

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Storage:儲存溫度<-20°C，可穩定保存6個月。請盡量減少凍融循環。

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Calculated Molecular Weight:33.6 kDa

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Endotoxin: 經 LAL 方法測定，每 μg 蛋白質含量 < 1.0 EU。

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Research Areas:免疫學、幹細胞、癌症、心血管

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Bio-activity:未驗證活動

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Formulation:以 20mM PB、150mM NaCl、pH 7.4 的 0.2 μm 過濾溶液形式提供。

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